American actor Eric Dane, widely known for his role as Dr. Mark “McSteamy” Sloan on Grey’s Anatomy, has died at the age of 53 following a battle with amyotrophic lateral sclerosis (ALS).
According to multiple international reports, Dane passed away on February 19, 2026, nearly a year after publicly revealing his ALS diagnosis. His family confirmed that he died surrounded by loved ones.
Dane announced in April 2025 that he had been diagnosed with ALS; a progressive neurodegenerative disease that attacks motor neurons in the brain and spinal cord. The condition gradually weakens muscles and affects voluntary movements, including walking, speaking, swallowing, and breathing. There is currently no known cure.
Best known for his breakout role on Grey’s Anatomy, Dane joined the long-running ABC medical drama in 2006 and quickly became a fan favourite for his charismatic portrayal of the confident plastic surgeon, earning the nickname “McSteamy.” He remained on the series until 2012 and reprised the role in later appearances.
Beyond Grey’s Anatomy, Dane built a diverse career in both television and film. He starred as Cal Jacobs in the HBO drama Euphoria, appearing alongside a new generation of actors and introducing himself to younger audiences. His film credits include roles in X‑Men: The Last Stand and Marley & Me.
Following news of his death, tributes poured in from colleagues and fans across the entertainment industry, with many remembering him as a talented performer and devoted family man.
ALS, sometimes referred to as Lou Gehrig’s disease, is a fatal condition that progressively destroys nerve cells responsible for muscle movement. While treatments can help manage symptoms, the disease continues to worsen over time.
Dane is survived by his wife and children.
His passing marks the loss of a television icon whose impact on medical drama and contemporary television spanned nearly two decades.
May his soul rest in peace.